C-Trap Dymo 400. Optical Tweezers-Fluorescence Microscope

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    "procurementMethodRationale": "This procurement is being undertaken via a single-source route due to the unique technical capabilities of the C-Trap\u00ae Dymo 400 and the exclusive rights held by its manufacturer, LUMICKS B.V.  the unique elements of this are:\n\u2022\tMulti-trap continuous-wave optical tweezers,\n\u2022\tMulti-colour confocal fluorescence microscopy, and\n\u2022\tMulti-channel laminar flow microfluidics.\nThese technologies are protected by several granted patents, including: US9952421, EP3256254B1 (optical traps), US9766180, EP3004848B1 (fluorescence imaging), S11156513B2 (optical force measurement) and EP3737756B1 (DNA supercoiling).\nNo other commercially available instrument can provide simultaneous, correlated force-distance-fluorescence measurements with the required resolution and sensitivity. \nKey performance features exclusive to the C-Trap include:\n\u2022\tForce resolution \u003c 0.1 pN and drift stability \u003c 0.3 pN over 2 minutes\n\u2022\tConfocal localisation precision \u003c 15 nm\n\u2022\tReal-time imaging of single molecules under physiological flow conditions\n\u2022\tEscape force \u003e 1000 pN, allowing for broad biological applicability\n\u2022\tIntegrated hardware/software for fast setup and automated experimental workflows.\nAdditionally, the system includes a complete service and application support package, exclusive training kits, and proprietary components that are not available from any other provider.",
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    "title": "C-Trap Dymo 400. Optical Tweezers-Fluorescence Microscope"
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